📝 Module 5 & 6 Practice
Multiple Choice Questions – attempt these before checking the Answer Key page
1. A person with genotype IAIB for the ABO blood group system has blood type AB. This is an example of:
A. Incomplete dominance
B. Co-dominance
C. Sex-linked inheritance
D. A somatic mutation
2. Which of the following is a germ-line mutation?
A. A mutation in a skin cell caused by UV exposure
B. A mutation in a sperm cell that is passed on to offspring
C. A mutation that only affects liver cells
D. A mutation that occurs after fertilisation in a body cell
3. CRISPR-Cas9 is best described as a technology that:
A. Clones whole organisms only
B. Allows precise editing of specific DNA sequences
C. Only works on bacterial cells
D. Produces genetically identical offspring through asexual reproduction
📝 Module 5 & 6 Practice
Short Answer Questions
Q1. Compare the processes and outcomes of artificial insemination and artificial pollination. (4 marks)
Q2. Explain how a mutation in a gamete-forming cell could introduce a new allele into a population’s gene pool. (5 marks)
Application Question (8 marks): A pedigree chart shows a family affected by a genetic disorder. Individuals I-1 (unaffected female) and I-2 (affected male) have three children: II-1 (affected female), II-2 (unaffected male), and II-3 (affected female). II-2 (unaffected) marries an unaffected woman (II-4) from outside the family, and they have one affected son (III-1). (a) Using the pattern shown across the pedigree, identify the most likely mode of inheritance (dominant/recessive, autosomal/sex-linked), and justify your answer using specific individuals from the chart. (5 marks) (b) Calculate the probability that a future child of II-2 and II-4 would be affected, showing your reasoning. (3 marks)
